Consideration Of Adding Preservatives in Sterile preparation.

 

Preservatives are not typically used for sterile preparations because the goal of sterile preparations is to completely eliminate all viable microorganisms, rather than simply inhibiting their growth or reducing their numbers. Sterile preparations must be completely free of viable microorganisms in order to prevent infections or other adverse reactions when they are administered to patients.

Preservatives are typically used in non-sterile preparations, such as topical creams or eye drops, to prevent the growth of microorganisms during storage and use. However, they are not effective at eliminating existing microorganisms, which is necessary for sterile preparations.

Instead of preservatives, sterile preparations are typically prepared under highly controlled conditions, using methods such as filtration, heat, and irradiation to sterilize the product and eliminate all viable microorganisms. The use of sterile techniques and equipment, as well as rigorous quality control testing, are also critical to ensure the product remains sterile throughout its shelf life.