Given below are the differences between Loss on Drying (LOD) and Moisture Content (MC) in the context of pharmacy: Aspect Loss on Drying (LOD) Moisture Content (MC) Definition The measurement of the weight loss of a substance upon drying The measurement of the water content within a substance Purpose Determines the volatile matter in a sample Quantifies the total water content in a sample Method Involves heating the sample to evaporate moisture Utilizes a variety of techniques to assess water content Measurement Reported as a percentage of the initial sample weight Reported as a percentage or absolute value of the sample weight Applicability Primarily used for substances that are prone to volatilize on drying Applicable to a wide range of substances, including liquids, solids, and s...